Team news
Manchester United are again expected to be without Jonny Evans, Mason Mount and Luke Shaw, although the latter is now back in group training.
Crystal Palace manager Oliver Glasner says Cheick Doucoure and Chadi Riad both require knee surgery and will miss the remainder of the season.
Eberechi Eze is ruled out of this match because of a niggling foot issue, with Glasner saying he wants the midfielder "pain-free so he can perform at his best".
However, long-term absentees Adam Wharton and Matheus Franca are set to return to the matchday squad.
Match facts
Head-to-head
Crystal Palace have won five of the past 11 top-flight encounters (D3, L3), including three of their last five trips to Old Trafford.
Manchester United are in danger of going four consecutive league matches without scoring against a particular opponent for the first time since a similar run versus Arsenal between 1981 and 1983.
Manchester United
The Red Devils are vying to win back-to-back league matches for the first time under Ruben Amorim.
They also have the chance to record consecutive clean sheets in the league for the first time since September, with the second game in that sequence a 0-0 draw at Crystal Palace.
United have failed to score a first-half goal in 17 top-flight games this season, more than any other side, netting 68% of their goals after the break (19 of 28).
The Reds are unbeaten in all 19 of their league and cup games this season when scoring first (W11, D8). Arsenal and Newcastle are the only other Premier League sides still undefeated in all competitions after opening the scoring.
Rasmus Hojlund has gone 12 consecutive league and cup appearances without scoring since netting twice against Viktoria Plzen on 12 December.
Crystal Palace
The Eagles have earned 13 Premier League away points since the start of December, more than any other side prior to the latest round of fixtures.
They are vying to win three consecutive top-flight away games for the first time since May 2019.
Oliver Glasner's side have conceded 11 Premier League away goals this term, fewer than any other side.
Romain Esse can become the fourth teenager to score in each of his first two Premier League appearances, emulating Alan Smith for Leeds and Federico Macheda and Anthony Martial for Manchester United.
Jean-Philippe Mateta has scored 21 goals in 36 appearances since Glasner took charge in February 2024.
