Tottenham made short and convincing work of a Fiorentina side who are flying high up in third in Serie A,

Image source, PA

Another significant substitution to tell you about - with 17-year-old Regan Poole coming on to make his debut, replacing Ander Herrera.

Andre Romer sees red for picking up a second booking.

Kevin Kilbane
Ex-Everton and Republic of Ireland winger at Old Trafford

"That was a penalty - the hand was in an unnatural position and gaining an advantage. The referee made a great decision."

The end is nigh. (As long as Juan Mata doesn't take the penalty.)

Memphis Depay's bending shot is palmed away by the outstretched arm of Kian Hansen,

Handball. Penalty.

Marcus Rashford to take it for his hat-trick?

Another change for Manchester United, more to run down the clock than anything else I'd imagine. Off goes Jesse Lingard, on comes Andreas Pereira.

One more Manchester United goal and it is goodbye Midjtylland. Juan Mata peels off to the left channel, looking up to see Jesse Lingard lurking. But the Spain midfielder cannot find his team-mate, allowing Midjtylland to nervously lump the ball clear. 

Six minutes to go....

Dele Alli - ruled out of the last-16 first leg after picking up a booking - departs to a standing ovation. Nabil Bentaleb is on in his place for the final five minutes.

Simon Stone
BBC Sport at Old Trafford

"See what I mean about emotions.

"From trawling the record books for most embarrassing Man Utd defeats in Europe, this is now set up to be a great European night.

"There are no trophies at stake - and seven games would still need to be played to win the tournament.

"But on a night when that pesky Law of Murphy has made another appearance, an 18-year-old is on the verge of becoming a hero."

In the aftermath of that Manchester United goal, I forgot to tell you that the home side made a sub. Young left-back Joe Riley, who has enjoyed a steady full debut without hitting the heights of team-mate Marcus Rashford, is replaced by Marcos Rojo. This is the Argentina defender's first appearance since the 0-0 draw at PSV Eindhoven back in late November.

Image source, Reuters

Shane Daly: Say what you want about LVG, he is giving our young players a chance. Thank you Louis.

Dennis Hobson: Goal!!!!! Local boy to local hero.

Sophie Gayter: Two goals on his debut for Rashford and Memphis playing with freedom? Not to worry LVG will stamp that out of them real quick.

Kevin Kilbane
Ex-Everton and Republic of Ireland winger at Old Trafford

"What a debut that is. Rashford might have sat on the bench all night had Martial not been injured in the warm-up.

"He has not looked out of place tonight. Everything he has done has been positive, his running and his touches on the ball.

"You get the feeling his team-mates want him to go on and core a hat-trick."

So Manchester United are now hurtling towards the last 16. But before you Red Devils fans get too excited, here's a word of warning. One more Midjtylland goal in the final 11 minutes will see them through on away goals. Stranger things have happened...

Dele Alli get clattered by Gonzalo Rodriguez. It is a cynical body check and should be a regulation free-kick for the hosts.

Instead the referee decides Alli has made a meal of it and makes an example of the Spurs man, issuing yellow.

That was plain wrong. And Alli will miss the first leg of the last-16 tie, presuming Spurs get there.

Ten to go.

Tottenham have cruise control engaged and their feet up on the dashboard.

The fight has gone out of the Fiorentina side.

And Erik Lamela has gone out of the Tottenham side. Joshua Onomah is on in his place.