Eric Dier is on for Spurs, he replaces £30m man Moussa Sissoko. Just 20 minutes left now. That penalty miss felt like a lifeline for Manchester City but they haven't threatened a response since. 

Burnley forward Andre Gray serves the second game of a four-match ban for comments he made on Twitter in 2012 so boss Sean Dyche keeps faith with the side that secured a 2-0 win over Watford on Monday.

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As expected, Arsenal midfielder Francis Coquelin has not recovered from the injury he sustained against Chelsea so manager Arsene Wenger is forced to make one change to the team which beat the Blues 3-0 last weekend, bringing in Granit Xhaka to fill the gap. 

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Matt Elliott
Former Leicester City captain at Kingpower Stadium for BBC Radio Leicester

Jamie Vardy looked a bit frustrated coming off. Some people might raise an eyebrow with that decision from Claudio Ranieri. Vardy looks a little bit unhappy. He doesn't want to come off and wants to be involved. I am surprised he's taken Vardy off. You wonder how Shinji Okazaki and Islam Slimani will pair up.

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Danny Drinkwater absolutely smashes in a shot from 25 yards after a corner was headed his way - but it is right down the throat of Fraser Forster. 

Phil McNulty
BBC Sport chief football writer at White Hart Lane

Pep Guardiola turned around in resignation alongside substitute Kelechi Iheanacho when that penalty was given - but there was a real spring in his step after Claudio Bravo saved from Erik Lamela and he prepared to send the young striker on.

Strangely, despite Spurs's domination, that penalty miss has caused a slight air of anxiety around White Hart Lane.

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The year doesn't end in a one but this Spurs team are playing some great football. Dele Alli and Son Heung-min link up again to move into the penalty area but this time the last-ditch tackle works. 

Leicester make a change - and it's Jamie Vardy who comes off. Shinji Okazaki is on. 

Matt Elliott
Former Leicester City captain at Kingpower Stadium for BBC Radio Leicester

What a great opportunity for Charlie Austin! It was an excellent save from Kasper Schmeichel so you have to give him a massive pat on the back. Leicester need to get stuck into Southampton. It's too comfortable for them. 

Great chance for Charlie Austin. A Virgil van Dijk pass puts him one-on-one with keeper Kasper Schmeichel and he goes for an ambitious chip which the Foxes keeper catches.

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Kelechi Iheanacho is now on for City, in place of Jesus Navas. Danny Rose is down having treatment after a bruising 50-50 with Raheem Sterling. 

Saved!

Claudio Bravo took a position really wide to one side as Erik Lamela prepared to take the spot kick, and it worked. Lamela's effort was not the best and Bravo dives to his left and saves!

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Earlier, we told you that City had never won a Premier League match having been two or more goals down at half-time.

Who was the draw against?

Liverpool in May 1996. City needed a win to avoid relegation.

Dele Alli drives into the box, Fernandinho makes a desperate challenge but all he can do is kick the midfielder in the shins. Penalty!

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Into the last half hour. Manchester City send for Kelechi Iheanacho. 

Steven Davis is on the edge of the box making a great tackle, and the Southampton midfielder makes a tackle before getting a shot off over the top. Good opening. 

Bishop Yinkus: I don't believe City has champion ability yet. But Guardiola's profile has put extra pressure on them to deliver. 

Mackson Wakama: On a good day Man City can score 3 goals in the 2nd half. But they are playing an excellent Spurs who are at home. 

Yogesh: Finally it looks like the Man City train is about to get derailed!

The work rate from Spurs has been immense and again they strip City of the ball within sight of their own goal, it's Victor Wanyama who nips in to take it from them, but Christian Eriksen's snapshot does not match the tackle and it's straight at Claudio Bravo. 

Matt Elliott
Former Leicester City captain

Southampton have been impressive, but they haven't tested Leicester goalkeeper Kasper Schmeichel that much and it's still goalless. Leicester manager Claudio Ranieri will have urged his players to lift themselves in his half-time talk. There's a bit of a break coming up for some players in the next week and he will have encouraged them to give it their all. There's no real tactical change from Leicester at this moment in time, though. Sometimes you have these games where you have to grind a result out.

Raheem Sterling loses the ball cheaply and then in his desire to get it back clatters Danny Rose and goes into the book. 

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Not the best game at Leicester so far. The champions have looked off the pace and Southampton will scent a second away win in seven days here.