Postpublished at 10:40 British Summer Time 14 October 2017
While we're talking team news, don't forget that your fantasy football deadline is looming large in your mirrors...
Listen to commentary on 5 live now - first of three commentaries
Second successive goalless draw in this fixture at Anfield
De Gea brilliantly denies Matip with his left foot
Liverpool keeper Mignolet then saves from Lukaku
Can fails to hit target from six yards
Tom Rostance
While we're talking team news, don't forget that your fantasy football deadline is looming large in your mirrors...
Burnley v West Ham (15:00 BST)
Burnley will again be without summer signing Jonathan Walters, who remains sidelined for the foreseeable future with a knee injury.
Nahki Wells and Dean Marney are both making progress from long-term injures but are not yet ready to return.
West Ham's only certain absentee is injured defender James Collins.
Javier Hernandez will be assessed after playing for Mexico in midweek, while Michail Antonio and Manuel Lanzini are available after injuries.
#bbcfootball or 81111 on text
Patrick O'Brien: Mourinho the Marvel. This year it's another two trophies in the cabinet; Premier and Champions League.
Wayne Hardy: Today we will see the difference in class between United and Liverpool. My prediction 4-1 Man Utd - if Liverpool are lucky.
Aleksander Pagels: I will never understand people who do not love football. Ever.
Join in! How do you rate the two managers on show at Anfield? Text 81111 (UK Only, names on) or tweet us at #bbcfootball.
Tottenham v Bournemouth (15:00 BST)
Tottenham defender Serge Aurier returns to the squad after serving a one-match suspension.
Left-back Danny Rose, midfielder Mousa Dembele and winger Erik Lamela have all returned to training but remain unavailable.
Bournemouth could be without forward Josh King and winger Ryan Fraser, who are both nursing hamstring problems.
Defender Brad Smith has been ruled out after picking up a hip injury while playing for Australia.
Crystal Palace v Chelsea (15:00 BST)
Simon Brotherton
MOTD commentator at Selhurst Park
When you're pointless and goalless after seven games, the last thing you need is to be striker-less. That remains the scenario for Crystal Palace, with Christian Benteke still sidelined as champions Chelsea head to Selhurst Park.
They will also be without Ruben Loftus-Cheek, who is ineligible to play against his parent club. His midfield influence will be missed.
Chelsea have injury issues of their own, with Alvaro Morata and N'Golo Kante both out, but Morata's absence up front could provide a decent opportunity for Michy Batshuayi.
He scored the winner away to Atletico Madrid recently but has found it hard to secure Antonio Conte's trust.
Crystal Palace v Chelsea (15:00 BST)
The last two seasons have been one's of continual, unbroken success for N'Golo Kante. The French midfielder has two Premier League winners medals and many more plaudits for his anchoring of Leicester's and then Chelsea's midfield.
However, Antonio Conte is going to have to do without him for three weeks after the 26-year-old limped out of France's 1-0 win against Bulgaria last weekend with a hamstring injury.
Conte revealed he is going for a scan next week and he is preparing for the next seven fixtures without arguably his most influential player.
Manchester City v Stoke (15:00 BST)
Sergio Aguero could well have Wolverine levels of recuperation. The Manchester City striker may turn out today for his club against Stoke, despite breaking a rib in a car crash just two weeks ago.
The 29-year-old striker was expected to be out for several weeks after the crash in Amsterdam on 29 September.
But the Argentina forward resumed full training on Thursday and "did quite well", according to the City manager.
When asked if Aguero would play, Guardiola said: "Maybe. He is not 100% but he has recovered quite well."
TV crews and snappers line the pitch at Anfield in preparation for the big day ahead.
But let's have a scout around now at the day's other games...
Liverpool v Manchester United (12:30 BST)
Juliette Ferrington
BBC Radio 5 live
Should be a proud day for Kenny Dalglish today; yesterday it was the official unveiling of the Kenny Dalglish stand at Anfield and today King Kenny is front cover of the matchday programme.
Liverpool v Manchester United (12:30 BST)
Two multi-million pound squads, one starting XI.
With Liverpool hosting Manchester United in the Premier League on Saturday, we merged both groups of players in our selector tool and asked you to pick the strongest side possible.
About 80,000 of you chose your preferred team, with Manchester United's players proving much more popular.
Only two of Liverpool's team made BBC Sport readers' starting line-up. But which two?
Liverpool v Manchester United (12:30 BST)
Guy Mowbray
Match of the Day commentator at Anfield
'It's only three points' seems to be Jose Mourinho's mantra, but that won't stop this being hyped as the biggest game around - which, in terms of worldwide interest, external, it might well be.
It comes at the same stage as last season's Anfield meeting, which was similarly ramped up but ended up being turgid, with United in full-on shut-up shop mode.
This HAS to be different, doesn't it?
This time Mourinho's goal-filled team will surely attack - but perhaps only after a stifling start. Expect Liverpool to go hard for the early goal to open it right up.
12.30pm starts can be slow burners in terms of atmosphere and action. This shouldn't be.
Liverpool v Manchester United (12:30 BST)
It is always a huge occasion and it is probably the type of fixture Liverpool need right now just to fire them up.
However, Liverpool have conceded an average of just under two goals a game in the league this season, so I am expecting United to score, especially with the form they are in.
Prediction: 1-1
Lawro's full predictions v rapper Wretch 32.
Think you can do better than Lawro? Predict the score for this match and the rest of this round's Premier League fixtures in our Predictor game.
#bbcfootball or 81111 on text
And, in interests of balance, how do you rate Jose Mourinho's spell in charge of Manchester United so far?
What has he done well? Was last season a disappointment? Can he win the league this season?
Ping us at 8111 (UK Only, names on) or tweet us at #bbcfootball.
#bbcfootball or 81111 on text
How highly do you rate Jurgen Klopp's two years at Anfield so far then? Is he the man to bring trophies back to Anfield?What would qualify as success for him this season?
Your Jurgen reviews please to 81111 (UK Only, with your names on) or tweet us at #bbcfootball
Liverpool v Manchester United (12:30 BST)
Two years after Jurgen Klopp was appointed as Liverpool manager, Reds fans and experts give their verdict on the job the German has done so far at Anfield.
Liverpool v Manchester United (12:30 BST)
Phil McNulty
BBC Sport chief football writer
When Jurgen Klopp made his first address to Liverpool fans after his appointment two years ago his message was clear.
"We have to change from doubters to believers," he told the club's official television channel before staring straight into camera, pointing his finger for added effect in the direction of those watching, and saying: "Now."
Klopp will celebrate the second anniversary of his arrival as Brendan Rodgers' successor with the visit of Jose Mourinho's Manchester United to Anfield on Saturday (12:30 BST kick-off).
Klopp's two years in charge are not reflected as a sharp uphill curve by statistics, but there is plenty of evidence - including his stellar work at Borussia Dortmund - that given time and support he will put Liverpool much closer to where they wish to be.
Read more from Phil on Klopp and Liverpool v Manchester United.
Liverpool v Manchester United (12:30 BST)
Liverpool will be without forward Sadio Mane, who faces a six-week absence with a hamstring injury suffered during international duty for Senegal.
Philippe Coutinho and Roberto Firmino are expected to be available despite a lengthy journey back from Chile.
Manchester United midfielder Marouane Fellaini injured knee ligaments playing for Belgium.
Captain Michael Carrick is doubtful with a calf injury but defender Phil Jones should recover from a knee issue.
Liverpool v Manchester United (12:30 BST)
Juliette Ferrington
BBC Radio 5 live
It’s an early start for 5live sport!
Liverpool are reliving past successes against Manchester United on the big screen outside the media entrance at Anfield. There’s been some absolute screamers flying in as the queue to get in gets bigger and bigger.
Chatting to United fans they say there’s a weird confidence today for all three points - but others are wary. One fan thinks United could have done with Liverpool winning at Newcastle before the international break because of the pressure on them to perform this lunchtime.
The big game is the early game today - but there's plenty to see for everyone. Seven Premier League games in total. Feast your eyes on this lot:
Liverpool v Manchester United (12:30 BST)
Burnley v West Ham (15:00 BST)
Crystal Palace v Chelsea (15:00 BST)
Manchester City v Stoke (15:00 BST)
Swansea v Huddersfield (15:00 BST)
Tottenham v Bournemouth (15:00 BST)
Watford v Arsenal (17:30 BST)
Liverpool v Manchester United (12:30 BST)
32 miles between them.
38 league titles between them.
What better way to welcome the Premier League back from the international break than a clash of the titans at Anfield?
Will Jose park the bus? How will Jurgen cope without one of his key attackers?Will a BIG game actually be a MUST see for once?
All shall be revealed...