Phil McNulty
BBC Sport chief football writer at Etihad Stadium

Plenty of eyebrows raised around Etihad Stadium that Manchester City manager Pep Guardiola has left Sergio Aguero on the bench as they chase at least three goals against Liverpool here tonight.

This may be a fitness issue, however, as there were still some doubts about whether he has fully recovered from a knee injury when he took his place on the bench against Manchester United.

Not a bad weapon to have, even as a substitute.

Ian Wright
Former Arsenal & England striker on BBC Radio 5 live

We know City are remarkable going forward but what they have shown in the last two games is that if you have a go at them they are vulnerable.

I don’t think Liverpool are going to park the bus. I don’t think either team can keep a clean sheet.

Image source, Rex Features

Predictions...

Former Arsenal and England striker Ian Wright is going for Manchester City to win 3-1 on the night. That's a 4-3 Liverpool win on aggregate.

Former Chelsea midfielder Andy Townsend thinks City will win 2-1. That will send Liverpool through to the semi-finals 4-2 on aggregate,

Juliette Ferrington
BBC Radio 5 live at Etihad Stadium

Image source, BBC Sport

Pep Guardiola says turning over such a deficit will be extremely difficult but by no means imposssible.

“Liverpool themselves won a UEFA Champions League trophy from the same position.”

He also says that in sport you have bad moments. “In these last two games we have had these moments and the opposition has scored goals.”

As we were sitting here setting up all the technical bits ahead of full commentary on BBC Radio 5live the PA system was in full rehearsal!

"This is our patch," is blasted, “this is our City”.

We can't talk about great comebacks without mentioning one of the greatest in the Champions League - the 2005 final.

Even Pep Guardiola's taken inspiration from how his side's opponents today turned that tie around.

Image source, Getty Images

Image source, Getty Images

Plenty of former Premier League players for Roma as they look to make a stunning turnaround.

Ex-Spurs defender Federico Fazio and former Manchester City players Aleksandar Kolarov and Edin Dzeko all start.

Roma XI: Allison, Manolas, Fazio, Jesus, Kolarov, Nainggolan, De Rossi, Strootman, Florenzi, Dzeko, Schick.

Barcelona field a strong team in Italy despite their comfortable advantage.

Philippe Coutinho is cup-tied so misses out and there is no Ousmane Dembele either. Lionel Messi leads the line.

Barca XI: Ter Stegen, Semedo, Pique, Umtiti, Alba, Busquets, Rakitic, Iniesta, Roberto, Suarez, Messi.

Dave: Wow, that is a crazy attacking line-up from Pep. I think he´s hoping to win 7-3 tonight.

Jon: Guardiola taking a leaf out of Gareth Southgate's book playing Kyle Walker at right centre back.

Despite Sergio Aguero starting on the bench, Manchester City boss Pep Guardiola names an attacking line-up.

There's four changes from the side that started the Manchester derby at the weekend. In come Kevin De Bruyne, Gabriel Jesus, Kyle Walker and Aymeric Laporte. Fabian Delph, Vincent Kompany, Ilkay Gundogan and Danilo make way.

David Silva captains the side.

Man City XI: Ederson, Walker, Otamendi, Laporte, Fernandinho, De Bruyne, Silva, Sane, Sterling, Bernardo, Jesus.

Liverpool make five changes to the side held to a goalless draw in the Merseyside derby.

Joining Mohamed Salah back in the starting line-up are Andrew Robertson, Trent Alexander-Arnold, Alex Oxlade-Chamberlain and Roberto Firmino.

Liverpool XI: Karius, Alexander-Arnold, Lovren, Van Dijk, Robertson, Wijnaldum, Milner, Oxlade-Chamberlain, Salah, Firmino, Mane.

Chris Waddle
Ex-England winger on BBC Radio 5 live

Sergio Aguero is obviously not fit enough. he would start, no doubt he brings goals. There must be a reason, obviously he is not fit enough.

Whatever team City puts out it is strong, Guardiola has a wonderful squad to pick from.

Ryan: I know City can do it - they have previous. They once came back from 3-0 down at half time to a Babayaro hatrick(!) against my 2000-01 Championship Manager Chelsea team to win 4-3

That team almost reminds of me when I'm losing in a cup match on Championship Manager and I just lob all my attacking players on for defenders.

If Manchester City come up short tonight, Pep Guardiola can't be accused of not going for it.

He's named an incredibly attacking line-up, even by Manchester City's high quality attacking standards.

Phil McNulty
BBC Sport chief football writer at Etihad Stadium

"Turning over such a deficit will be difficult but by no means impossible."

These are the words of Manchester City manager Pep Guardiola in his match notes as they try to over-turn Liverpool's 3-0 lead in the second leg of this Champions League quarter-final.

It will take all of City's attacking prowess to claw back that deficit but they have that quality - the doubts come when they are asked questions in defence and six goals conceded in their last two games against Liverpool and Manchester United strike an ominous note.

Not sure this one is set up as a goalless draw.

It's all very calm and low key as the Liverpool bus arrives at the stadium...

Image source, Getty Images

Image source, Reuters

Bezaleel: Manchester City will have to play the game of their lives tonight. Unfortunately they are playing a team that knows what COMEBACK means and what it entails.

Anon: Even as a City fan, I know we can't overturn this, Liverpool would have to collapse, we needed a goal at Anfield. Could still be a good match though.

Manchester City make four changes from the weekend but Sergio Aguero is on the bench.

Meanwhile, Mohamed Salah returns for Liverpool.

Full team news to follow.

Final Score

You can listen to our Champions League commentary tonight and watch all the scores as they come in across the English & Scottish leagues.

Press the Red Button on your TV or go to the BBC Sport website and click on 5 live Final Score.

Manchester City are not the only team hoping to produce a stunning comeback in the Champions League tonight.

Roma host Barcelona having lost the first leg 4-1 at the Nou Camp.

"Why not believe until the end and hope we can achieve something unprecedented?" said Roma boss Eusebio di Francesco.

"It's a really tough ask, but we have the duty to try."

Fair point. Although, as ever with Barcelona, the performance of the man below will have a big say on Roma's chances of an upset.

Image source, Getty Images

I'm quite surprised by the optimism of a few people in the office regarding Manchester City's chances tonight. I can't help but feel that failing to grab an away goal will prove crucial but others I've spoken to are pretty convinced City will stage one of the great comebacks to progress.

So what do you think? Can you see a Manchester City comeback or do you think Liverpool have done enough already to secure their place in the semi-finals?

Let us know your thoughts via #bbcfootball or text in on 81111 (UK only)

Stephen Warnock
Ex-Liverpool defender at Etihad Stadium

I feel that Manchester City will score first and it will be tough for Liverpool at the start, but then I think Liverpool will score on the break. That will deflate City and even though I feel Manchester City will win on the night, Liverpool go through on aggregate.