Robbie Savage
Ex-Wales midfielder on BBC Radio 5 Live

Incredible run - but the run had to come to an end and it's come to an end against their opponents from across the city. They're still the best team in the country and got a great opportunity to still win all four competitions they're involved in.

United have been very good today let's take nothing away from them. The way they've moved, the counter attacking football and the way they've nullified City. City have been off today - Kevin de Bruyne and Ilkay Gundogan have been ineffective and Sterling has missed a couple of chances. It's just been United's day.

Image source, EPA

All over and Manchester City's winning run comes to an end at an incredible 21 games.

An excellent and deserved win for Manchester United, who put in a display brimming with attacking intent and dogged determination to see it out.

One last attack for Manchester City as Riyad Mahrez's shot is batted away by Dean Henderson.

Final change for Manchester United as they look to see this one out. Brandon Williams is on for Bruno Fernandes.

Image source, Reuters

Can Manchester City find two goals in five minutes? That's how much has been added at the end of the 90.

Manchester United are closing this out pretty comfortably it has to be said, however.

Another change for Manchester United as Nemanja Matic comes on for Anthony Martial.

Image source, BBC Sport

Tottenham manager Jose Mourinho makes three changes to the side that started their 1-0 win over Fulham on Thursday.

Dele Alli, Ben Davies and Tanguy Ndombele drop to the bench with Sergio Reguilon, Harry Winks and Lucas Moura all starting.

Tottenham XI: Lloris, Doherty, Alderweireld, Sanchez, Reguilon, Winks, Hojbjerg, Moura, Bale, Son, Kane

Subs: Hart, Lamela, Dier, Sissoko, Alli, Bergwijn, Ndombele, Davies, Vinicius

Image source, BBC Sport

Crystal Palace boss Roy Hodgson makes one tweak to the side from that began their 0-0 draw against Manchester United on Wednesday. James McCarthy has a groin injury so Jairo Riedewald starts in his place.

There’s also a place on the bench for Wilfried Zaha, who has missed the last five games with a hamstring problem.

Crystal Palace XI: Guaita, Ward, Kouyate, Cahill, Van Aanholt, Milivojevic, Riedewald, Townsend, Eze, Ayew, Benteke.

Subs: Butland, Dann, Zaha, Mateta, Schlupp, Wickham, Batshuayi, Kelly, Hannam

StanTheMan: Definitely not an off day for City. Let's all credit Ole here. He has his tactics. If only we didn't drop those silly points.

Jason: United’s form in between this match against City has probably cost them the title. Attitude and consistency is much more important than talent.

John Bathgate: Whenever a top team loses it's because they had an off day - it's never because the other team were better

It is going to take something special for Manchester City to maintain their winning run with just a few minutes left. If indeed it is to come to an end, what a run it has been.

They are still plugging away, though, as Ilkay Gündogan flicks on a corner but John Stones can't get the touch at the back post.

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In comes another cross from Kyle Walker. Victor Lindelof falls over and Raheem Sterling has a free header... wide.

Manchester City have managed just one shot on target in the second half so far - in the 51st minute.

They are doing all the attacking at the moment but the Manchester United defence looks comfortable.

Sergio Aguero remains in his seat with his big coat on. Manchester City need two goals but it doesn't like the striker will be turned to any time soon.

Robbie Savage
Ex-Wales midfielder on BBC Radio 5 Live

Got to score there Raheem Sterling what a ball from Kyle Walker - Sterling makes a good run on Victor Lindelof's shoulder, Lindelof misses it and Sterling is four-yards out and just misses it on the half volley. He has got to score there.

Kyle Walker was screaming at his team-mates to cross before he came on and the first chance he has he puts in a belter of a ball. Expect more of them in the final few minutes.

What a chance!

Kyle Walker swings in a brilliant cross but Victor Lindelof gets the slightest of touches to deflect the ball through Raheem Sterling's legs as the forward looked certain to stab in from close range.

Robbie Savage
Ex-Wales midfielder on BBC Radio 5 Live

Brilliant play from Phil Foden, dynamic, direct, driving into the heart of Man United. Back to goal with the first touch and as he turns and hits it Raheem Sterling threw a leg at it but couldn't make any contact. Better from Man City.

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Phil Foden is straight into the action as he drives forward but is just unable to apply the finish the positive run deserved.

Ole Gunnar Solskjaer tells Dean Henderson to hit the ball out of play because Marcus Rashford can't continue. Manchester City take the throw quickly, though, and Solskjaer and Pep Guardiola exchange words about it on the touchline.

Solskjaer doesn't have much longer to wait to make the change, though, and Mason Greenwood comes on.