Time is ticking away and any hope of a late Arsenal fightback is beginning to fade in Eindhoven.

The hosts have a corner, but it's long and Luuk de Jong can't reach it.

It looks like the striker might have injured himself stretching for that.

Cody Gakpo is applauded off as he's replaced by Mauro Junior.

He was denied a brilliant goal in the first half, in another exciting performance that will surely not have gone unnoticed at clubs across Europe.

GoonerThoughts: The over reaction from Arsenal “fans” is laughable.. 5 wins and 1 loss in Europa League, top of Premier League. And then comments like Dave’s saying CL droppers would have a field day. So over the top. I’m sure Arteta will note where he needs to strengthen.

Anon: Give it a rest Dave, talk about doom and gloom.

Anon: Dave knows Arsenal have already qualified right??

Arsenal continue to try and ask questions, but PSV continue to provide the answers.

Bukayo Saka takes a tumble as he threatens to make his way into the penalty area, but the referee tells him to get up and crack on.

A triple change for PSV now as Ruud van Nistelrooy looks to see out what would be an excellent victory over the Premier League leaders.

Granit Xhaka looks to offer Xavi Simmons help in getting off the pitch, which inevitably doesn't go down well. Both players get themselves a yellow card, and after a prolonged farewell Simons eventually departs.

Noni Madueke, Jordan Teze and Guus Til come on, as Joey Veerman and Jarrad Branthwaite also make way.

What a tackle!

Jarrad Branthwaite produces a superb last-ditch tackle to deny an almost certain Arsenal goal, nipping in to beat Gabriel Jesus to the ball inside the six-yard box.

Arsenal are building pressure on the PSV goal but there's no way through just yet. The hosts are working hard to protect their lead and they're so far succeeding in frustrating Mikel Arteta's side.

Image source, Getty Images

Gabriel and Ben White come on as Mikel Arteta looks to deal with his Luuk de Jong problem.

Kieran Tierney and Takehiro Tomiyasu make way.

Arsenal settle back into possession after weathering a PSV storm, but it's not long before the hosts are nipping away to try and create another opportunity on the counter.

The Gunners are yet to land a shot on target so far in the second half.

Arsenal are not handling Luuk de Jong at all!

The half-time substitute is only denied by an excellent Aaron Ramsdale save at close range.

The flag goes up, so it wouldn't have counted, but PSV will feel they really should be out of sight by now.

Blimey, PSV go close to a third again but Luuk de Jong fires wide of the far post.

Gabriel Martinelli and Phillipp Mwene both receive yellow cards following a disagreement.

Here comes Gabriel Jesus.

The Brazil forward replaces Rob Holding for the final 25 minutes or so.

Simon Stone
BBC Sport at Old Trafford

There has been a growing clamour for Manchester United boss Erik ten Hag to make more use of 18-year-old Alejandro Garnacho.

The youngster has already been called up by the full Argentina national squad and was instrumental in United's FA Youth Cup success last term.

Garnacho's three substitute appearances so far this season total just 21 minutes.

It will be fascinating to see how he goes on this evening.

A THIRD goal disallowed for offside for PSV!

Cody Gakpo meets a cross in the box and knocks the ball past Aaron Ramsdale, but immediately the flag is raised.

It's all PSV.

That's exactly how PSV want to play this now.

The hosts invite the pressure and then look to pounce on the counter. Arsenal look a bit stretched, but they recover.

Still, the hosts will have a corner...

Kieran Tierney goes into the book for a late tackle. It's all a bit more rushed from Arsenal now as they try and force their way back into this. PSV have dropped in to avoid conceding a quick leveller.

Bukayo Saka and Thomas Partey are sent on by Mikel Arteta, with Martin Odegaard and Albert Sambi Lokonga making way.