Fast start by Palace.

Eberechi Eze goes close for the second time as West Ham are caught out at the back.

He should have done better with that. That was a big chance but Eze screws it wide.

New manager for Villa and a new captain for United.

But it's been a slow start at Villa Park. It's absolutely tipping it down and both sets of players are finding the conditions tricky.

That little move from Newcastle right now just shows the confidence pumping through their veins right now. It was bold and brilliantly executed.

Oh, superb move and almost a superb goal!

With some slick one-touch play, Newcastle pick open Southampton down the right before a cross into the middle drifts tantalisingly ahead of Callum Wilson.

Gavin Bazunu dived to try and get it but got nowhere near.

Nervous moments for Lukasz Fabianski.

A free-kick by Eberechi Eze just outside the box is on target and the West Ham keeper spills it before pouncing on the loose ball before anyone can get to it.

Long throws are all the rage again.

We saw Thomas Partey bombing them in for Arsenal earlier and now Mohammed Salisu is slinging them in for Saints.

Newcastle deal with the first one well enough.

A massive roar when Unai Emery's name was read out over the speakers moments before kick-off at Villa Park.

The Spaniard responded by applauding all four sides of the ground.

They're desperate for success in this neck of the woods. Will Villa come good under the new boss?

The away fans are in fine voice.

As well they should be. They're on the crest of a wave right now.

This is a big game for both these sides, for different reasons.

Saints need the points to boost their battle against the drop, Newcastle are pushing for the top four.

Eddie Howe's side know points earned here, pulls them further ahead of the likes of Chelsea after their defeat.

No time to waste. The football comes thick and fast today.

The three games at 2pm are getting under way.

Image source, Getty Images

It's just 407 days since Aston Villa won 1-0 at Old Trafford thanks to an 88th-minute Kortney Hause goal.

Since then Villa have got rid of Dean Smith, appointed Steven Gerrard, got rid of Gerrard and appointed Unai Emery.

Since then, United have got rid of Ole Gunnar Solskjaer, appointed Ralf Rangnick, allowed Rangnick to leave and appointed Erik ten Hag.

Image source, Getty Images

It's got its detractors but are West Ham fans finally warming to the London Stadium?

The Hammers have won their past six domestic and European games at the venue.

Will they make it seven in a row at home?

Crystal Palace have not won a top-flight away game since 30 April and have not scored away from home in the Premier League since 27 August.

But the Eagles have taken 10 points from the last 15 available.

A fascinating London derby awaits.

Aston Villa

Image source, Getty Images

Aston Villa boss Unai Emery, speaking to BBC Sport:

"We are ready to play and start together. It's step-by-step. Our target is clear, to start today and think about winning. We are so excited to start in front of our own fans."

Newcastle United

Newcastle manager Eddie Howe, speaking to Sky Sports, on what has impressed him the most about his side's recent form: "A combination of a lot of different things, our attitude and mindset has been excellent, we've been brave and attacked the games."

On Jacob Murphy starting with Joelinton suspended: "Jacob he has been excellent in recent weeks, unlucky to lose place to Joelinton when he came back from injury.

"In the last game had a quick cameo for 20 minutes and was electric - quick, direct and a had a number of attempts on goal. I hope to see that again today."

Manchester United

Image source, Reuters

Manchester United boss Erik ten Hag has been speaking pre-match about giving Cristiano Ronaldo the captain's armband less than three weeks after leaving Old Trafford before full-time.

"Nothing has changed," says Ten Hag.

"When you are captain and leader you have to be an example and that is what I expect for him on the pitch.

"He is an important part of the squad, we've said that since the start of the season. He has to take even more the leader role because Harry Maguire is on the bench, Bruno Fernandes is suspended, so it is up to him."

One game down. Four more to come including three that are moments away from kick-off.

So, Arsenal are back on top of the Premier League. Two points clear of Manchester City.

If the Gunners win at Wolves next Saturday, they will go into the World Cup break at the summit.

Exciting times.

Mark Schwarzer
Former Middlesbrough & Fulham keeper on BBC Radio 5 Live

Arsenal have been the better side, certainly in this second half. They have dominated for large parts of it. Chelsea have looked disorganised, they haven't really had a chance to get in the game. Aubameyang has come off, they really have struggled. Broja up front has struggled to keep hold of the ball, he's been off side a few times they're have really struggled to get going but a lot of that is down to the fact that Arsenal put a lot of pressure on them and are certainly high on confidence.

A huge win for Arsenal!

They had to battle for it, but they were the better side here. Gabriel's point-blank finish from Bukayo Saka's corner settles it.

The Gunners replace Manchester City at the top again.