Half-timepublished at 17:35 British Summer Time 2 September 2017
London Irish 21-10 Harlequins
Irish stand firm to go in at the break with a healthy lead.
It's been thoroughly entertaining so far. The second half is set up nicely.
FT: London Irish 39-29 Harlequins
Ojo, Bell, Treviranus and McKibbin score tries for Irish, Bell kicks 19 points
Marchant, Yarde, Care and Walker reply for Quins; Brown sin-binned late on
FT: Saracens 55-24 Northampton
Maitland (3), Barritt, Wigglesworth, Lozowski, Koch, Brits and Spencer with tries for Sarries
Wood scores twice in reply for Northampton
FT Wasps 50-35 Sale
Robson (4), Wade, Rowlands and Rieder with tries for Wasps
McGuigan, Ben Curry, Solomona, De Klerk and Strauss reply for Sale
Owen Phillips
London Irish 21-10 Harlequins
Irish stand firm to go in at the break with a healthy lead.
It's been thoroughly entertaining so far. The second half is set up nicely.
London Irish 21-10 Harlequins
The lineout comes to nothing as Mike Brown fails to collect a pass at speed as they move the ball from left to right.
But they have another penalty.
London Irish 21-10 Harlequins
Harlequins are probing in the dying embers of the first half. They have a penalty and kick for the corner.
London Irish 21-10 Harlequins
Tommy Bell had another kick at goal and this time he knocks it over.
Irish now lead by 11 with just a couple of minutes to go until the break. They have deserved their advantage.
London Irish 18-10 Harlequins
Quins have their first try. A brilliant line from Joe Marchant who collects a short pass from Jamie Roberts 20 metres out and darts over unopposed.
Marcus Smith slots his second kick of the afternoon, opting to drop-kick over the conversion.
Chris Jones
BBC 5 live rugby union commentator
Fair play to London Irish. They have scored two tries, one from a cross-kick from inside their own 22 and the other from an offload from Blair Cowan.
They are making an excellent first fist of their return to the Premiership.
Harlequins need to summon their international experience to work their way back into this game.
London Irish 18-3 Harlequins
Some disjointed midfield play sees both side pumping the ball away from danger but ends with a second London Irish try.
That's magnificent hands from Blair Cowan. He is on the ground but somehow flips the ball up Tommy Bell who evades a couple of challenges and crosses over in the corner.
Bell fails to convert his own try but it's been super stuff from the Exiles so far.
London Irish 13-3 Harlequins
Topsy Ojo has another sight of the Quins line but knocks on.
The London Irish winger has pace in abundance as we know and is showing it at Twickenham. He could easily have had a second try there.
Paul Grayson
Former England fly-half on BBC Radio 5 live
That's a magnificent try, counter attacking at its best.
Jamie Roberts tried to crash the ball up and got nailed. The turnover was on but you have to execute.
It was a brilliant, breathtaking try which should be on a highlights reel.
London Irish 13-3 Harlequins
A stunning try by Topsy Ojo, who collects a really cute kick from James Marshall and steams almost the length of the pitch, exchanges passes with Fergus Mulchrone and goes over in the corner.
It's a wonderful try that is awarded by the TMO after being checked for offside and a knock on.
Tommy Bell adds the extras.
London Irish 6-3 Harlequins
Nearly. So nearly for Harlequins.
Flying winger Charlie Walker juggles with ball after some great work by Danny Care and Marcus Smith (pictured) gives him a sight of the line.
But some fine last-ditch defence denies him and Irish survive.
London Irish 6-3 Harlequins
That's stunning footwork by London Irish wing Alex Lewington out wide.
Real dancing feet sees him elude Quins' England full-back Mike Brown but he is knocked off balance and cannot find a colleague.
Maybe we used up all the tries in the earlier games. Greedy.
London Irish 6-3 Harlequins
London Irish have the chance to regain their six-point lead with a third Tommy Bell penalty.
But he is off target with one he ought to have slotted.
London Irish 6-3 Harlequins
London Irish fail to deal with a driving mau and are penalised for coming around the side.
Marcus Smith kicks the penalty from on the 22. A great start for the 18-year-old. What nerves?
Wasps 50-35 Sale
Nathan Hughes boots the ball into touch as the clock goes red and Wasps are up and running with a seven try to five victory over Sale.
A thrilling start to the season at the Ricoh.
"Dai Young will be pleased with the bonus point and the tries. To start of your campaign with a win after the disappointment of last season is good," said BBC Coventry & Warwickshire's summariser Richard Moon.
London Irish 6-0 Harlequins
London Irish repel the first threat.
Scrum-half Scott Steele whacks the ball clear. Quins come again. Danny Care has a sniff of a break but it comes to nothing.
Wasps 50-35 Sale
This will be no more than a consolation for Sale but they may have scored the final try of the afternoon.
New arrival Josh Strauss goes over for their fifth score and AJ MacGinty converts.
What will they be thinking, though, scoring five tries away from home and still ending up on the losing side?
London Irish 6-0 Harlequins
Quins haven't got going but have a good platform with a scrum just inside the Irish half.
The burly figure of Jamie Roberts crashes through a couple of challenges in typical fashion and there is some good pressure from Quins now.
London Irish 6-0 Harlequins
Tommy Bell slots his second kick. It's quite straightforward, just off centre. The early pressure on the Quins defence is telling.
Wasps 50-28 Sale
And that really will be that. It has been nip and tuck for a while but flanker Alex Rieder scores Wasps' seventh try after a break by Gaby Lovobalavu.
Jimmy Gopperth's conversion brings up the home side's half-century of points.