Bundee Aki has gone off to get a cut on his cheek patched up. The powerhouse centre came galloping out of the line to clatter Finn Russell in that last attacking phase. The Scotland fly-half bounced up and carried on - Aki copped a sore one.

Josh van der Flier is also off to have a blood injury taken care of. Jack Conan comes on.

And, slightly worryingly for the Irish fans, Johnny Sexton was receiving a little treatment while Laidlaw slotted that penalty.

Over she goes. Scotland, at last, have something.

Finally, Scotland get some attacking ball in Irish territory. Stuart Hogg releases Tommy Seymour up the right touchline, and the wing bursts into the 22.

Jonny Gray and WP Nel take it on a bit further before Ireland enter the ruck from the side. Greig Laidlaw will line up the penalty shot to get his team on the board.

Andy Burke
BBC Scotland at the International Stadium Yokohama

There are sections of green jerseys all over the stadium and the Irish fans are in fine voice now as their side take a firm grip on this match.

It’s hard to pick out the Scotland jerseys in the stands and those wearing them on the pitch are coming off second best so far.

Twelve points down against a team like Ireland represents a huge test of their mettle.

Rory Lawson
Former Scotland captain

Tony Ward
Former Ireland fly-half on BBC Radio Ulster

The television pictures have just cut to the Scotland coaches box, where Gregor Townsend's face is a picture of frustration. I wonder what Townsend might have up his sleeve to deal with the Irish onslaught. His team haven't had a sniff so far.

That's an 11th try for 37-year-old Best in his 121st Ireland cap.

Ireland put the penalty to the corner, but Hamish Watson stifles their attacking momentum.

There's an earlier infringement by Ryan Wilson, though, and back we come for another penalty. The Scotland vice-captain rumbled into a maul from the side.

This one is deep in the Scottish 22 and very kickable. Ireland aren't kicking it, though. Into the corner it goes. They reckon they've got Scotland on the ropes.

Tony Ward
Former Ireland fly-half on BBC Radio Ulster

Ireland get one-up at the breakdown too with a smart bit of jackaling.

The turned-over ball finds Jordan Larmour who has incredible pace, but stumbles as he approaches Stuart Hogg. Sexton's kick is marked inside the 22, Sean Maitland boots it away and Sexton returns the compliment.

Ireland win another turnover, this time Bundee Aki jackaling and earning his side a penalty. Ireland are winning all the small battles just now.

Image source, Reuters

Rory Lawson
Former Scotland captain

Stuart Hogg is kicking a lot in these opening minutes. This one, from around halfway, bounces a couple of yards too far and is dotted down for a 22m drop-out.

Meanwhile, Peter O'Mahony is down receiving some treatment.

Lovely stuff from Ireland off that line-out as Rory Best releases Murray, whose chip kick is gathered by the retreating Jonny Gray of all people.

Ireland recover possession and Iain Henderson thunders deep into the Scottish 22. This looks promising for the Irish...

Tom English
BBC Scotland's chief sports writer

What a harem-scarem opening few minutes. Scotland over-throw the first line-out, Johnny Sexton gets charged down, then Ireland knock it on.

Stuart Hogg threatens on the counter and then probes a lovely kick into the Irish 22. Ireland get the line-out working and clear up to halfway, and now Scotland come again, but Duncan Taylor's pass is too far ahead of Sean Maitland and Ireland will throw in just inside the Scottish half.

Wayne Barnes, the vastly experienced Engilshman in charge, blows his whistle and Stuart Hogg gets this colossal clash under way.

Chris Henry
Former Ireland flanker on BBC Radio 5 Live Sports Extra