And the game's first scrum goes Wales' way.

That has been one of the few pluses for Wales this campaign and shows the impact of scrum coach Adam Jones.

Wales would love to him out there today!

Wales get their first carry but prop WillGriff John is penalised for not releasing and again England have the chance to pump the ball up field.

But Luke Cowan-Dickie is off with his throw and we have the game's first scrum midway in the Wales half.

Danny Care
Former England scrum-half on BBC One

The players would've had their meeting last night and said 'let's have a big start, a fast start', that's exactly what they've done, let's see if they can continue their momentum.

Jonathan Davies
Former Wales international on BBC One

It's such a great start by England.

They showed their intent, but what a kick by Smith, that's the kick that set it all up, it was brave and it's an easy finish for Itoje.

Gareth Griffiths
BBC Sport Wales at Principality Stadium

In 2015, Wales were piling on the points against Italy in Rome on 'Super Saturday' to try and win the title.

They didn't that year with Ireland triumphing but they were in contention. A decade on they are battling with the Italians to finish bottom. How times change.

After Italy's 22-17 defeat against Ireland, Wales now know they need two match points to avoid a second successive Wooden Spoon.

First minute, first penalty to England and the first strains of Sweet Chariots.

So then.... what way does this one go?

And we're off....

Wales: 15-Murray, 14- Roberts, 13-Llewellyn, 12-B Thomas, 11-Mee; 10-Anscombe, 9-T Williams; 1-N Smith, 2-Dee, 3-John, 4-Rowlands, 5-Jenkins, 6-Wainwright, 7-Morgan (capt) 8-Faletau.

England: 15-Smith, 14-Roebuck, 13-Freeman, 12-Dingwall, 11-Daly; 10-F Smith, 9-Mitchell; 1-Genge, 2-Cowan-Dickie, 3-Stuart, 4-Itoje (capt), 5-Chessum, 6-T Curry, 7-B Curry, 8-Earl.

Replacements: 16-George, 17-Baxter, 18-Heyes, 19-Cunningham-South, 20-Pollock, 21-Willis, 22-Van Poortvliet, 23-Ford

Image source, Huw Evans Picture Agency

This is the 143rd meeting between these bitter rivals and England lead the series 69-61 with 12 games drawn.

Head-to-head

• England have won four of the last five Tests
• England have won nine of their last 11 in the Six Nations - including the last three in a row.
• However, seven of those nine victories have come by single digit margins.

• The Red Rose have not scored four or more tries away to Wales in the Championship since their very first clash at the Principality Stadium in 2001.
• Wales lead the series 9-7 at the Principality Stadium

First it's God Save the King.

And now Mae Hen Wlad Fy Nhadau.

Oh that's got the goosebumps going!

Image source, Getty Images

Alun Wyn Jones
Former Wales captain on BBC One

On these days all roads lead to Cardiff.

There is only one place I'd like to be other than right here and that's the other side of that white line.

It's an opportunity for these players to write another page in the history books. There's an interesting backdrop, and whatever happens won't paper over any cracks, but it's their opportunity to leave this tournament with a win.

The Principality Stadium falls silent to mark 75 years since a plane crash on a scale the world had never seen before happened in a tiny Welsh village.

The aircraft had been packed full of jubilant rugby fans on their way home from seeing Wales beat Ireland on 12 March 1950.

But just short of its final destination at Llandow Airfield in the Vale of Glamorgan, the plane crashed - killing 80 of the 83 people on board. It was, at the time, the world's worst air disaster.

Mike Henson
BBC Sport at the Principality Stadium

Image source, BBC Sport

It is cooking up nicely under the Principality roof.

Former Wales flanker Josh Navidi has just been interviewed pitchside and referred to England wing-turned-centre as 'Tommy Fleetwood'.

A slip of the tonge or a twist of the knife? Probably the former, but nice it imagine it was the latter...

Danny Care
Former England scrum-half on BBC One

It's a unique occasion. I can enjoy it for the first time ever, it's incredible.

These are the games you want to play in, these games make or break dreams. There's a Lions tour to go for, but firstly for England there's a championship to go for.

If you look at all the stats you'd say England should come here and win comfortably, but something happens here when that roof is closed.

I'm nervous.

Wales interim head coach Matt Sherratt: "If that win comes it would give everyone a massive lift, especially against England at home.

"I would love to sign off [with a win], not for me but for the players and staff who have been here for a long time. It would be huge for them. It's important that it's not something we talk about a huge amount in camp or you can get a bit desperate.

"There'll be emotion on Saturday but it's about getting that balance between heart and brain. There'll be stacks of heart but we need to get our game on the pitch."

England head coach Steve Borthwick: "Our aspiration is to win the tournament, that has always been the target and that has not changed. The team is really clear on what we need to do to put ourselves in that position."

"We want to do it by playing fast and getting the ball to our players with strength, pace and athleticism. That is exactly how we want to play this weekend."

So according to the official Six Nations website, England have a 78% win probability today.

Wales fans... agree with that?

Hit the thumbs.