Image source, Getty Images

Marcus Smith returns to England's starting XV at full-back and Tommy Freeman moves to outside centre.

Smith is reinstated at 15 after missing out on a start in England's comfortable win over Italy and Freeman, who has made all 19 of his Test appearances on the wing, steps into midfield to replace the injured Ollie Lawrence.

In a reshuffle to the backline, Elliot Daly moves to the wing, while Tom Roebuck replaces Ollie Sleightholme on the other.

Borthwick makes two changes in the forwards as Ben Curry partners his twin Tom on the flank, with Ben Earl switching back to number eight, while Luke Cowan-Dickie will start at hooker.

In the front row, prop Will Stuart will win his 50th Test cap.

The visitors have opted for a six-two spilt of forwards and backs among their replacements and promising young back row Henry Pollock could make his Test debut from the bench.

Veteran fly-half George Ford is also named among the replacements for the first time in this year's tournament, and will win his 99th cap if he comes off the bench.

England: M Smith; Roebuck, Freeman, Dingwall, Daly; F Smith, Mitchell; Genge, Cowan-Dickie, Stuart, Itoje (capt), Chessum, T Curry, B Curry, Earl.

Replacements: George, Baxter, Heyes, Cunningham-South, Pollock, Willis, Van Poortvliet, Ford.

Image source, Huw Evans Picture Agency

Wales have brought in Joe Roberts and Aaron Wainwright as two starting changes.

Scarlets centre Roberts will make his first professional start on the wing as he replaces the injured Tom Rogers.

Roberts impressed after coming on as a 10th-minute replacement in the 35-29 defeat by Scotland at Murrayfield.

Wainwright will pack down in the back row instead of Tommy Reffell who drops down to the replacements bench, which also includes Saracens centre Nick Tompkins for his first appearance of this year's tournament.

Wales: Murray; Mee, Llewellyn, B Thomas, Roberts; Anscombe, Tomos Williams; Smith, Dee, John, Rowlands, Jenkins, Wainwright, Morgan (capt), Faletau.

Replacements: Lake, G Thomas, Assiratti, Teddy Williams, Reffell, R Williams, J Evans, Tompkins.

Image source, Huw Evans Picture Agency

It's part two of Super Saturday and one of those fixtures that rarely disappoints.

Life could not be more different rugby wise either side of Offa's Dyke right now.

England are fighting for the Six Nations title but that is like a red rag to a bull - or a rag to a red dragon - for Wales to end their miserable losing run.

Things are starting to click for the Red Roses under Steve Borthwick with three wins on the bounce against France, Scotland and Italy.

But their run of three away defeats in the championship is their longest since a four-game streak between 2006 to 2007.

Wales are in the grip of the worst losing run in their history after 16 defeats in a row.

But the last three have been by single-digit margins and there is nothing quite like facing the old enemy that rouses those red jerseys.

Both head coaches have been forced to tweak their line-ups following injuries, as Wales put a centre on the wing and England switch a wing to the centre.

So first, let's take a look at today's teams.