Team news
Southampton defenders Jan Bednarek, Taylor Harwood-Bellis and James Bree have been passed fit to play.
Will Smallbone is unavailable because of the groin injury that forced him to withdraw from international duty with the Republic of Ireland.
Crystal Palace defender Chris Richards is ruled out with a calf issue but top scorer Jean-Philippe Mateta is available, having made his comeback from a head injury at Fulham on Saturday.
Will Hughes, who missed that FA Cup tie through illness, completes a two-game ban affecting only Premier League matches, while Chadi Riad and Cheick Doucoure are long-term absentees.
Match facts
Head-to-head
Crystal Palace are vying for a fifth consecutive Premier League victory against Southampton.
Saints have lost their past two top-flight home games against the Eagles, as many defeats as in their first 21 such meetings (W14, D5).
Southampton
Saints have lost their last nine league matches at St Mary's. The only teams to record longer losing runs at home in a single top-flight season are Birmingham City (10 games in 1985-86) and Watford (11 matches in 2021-22).
They have lost 14 of their past 16 top-flight fixtures.
November's 1-1 draw at Brighton is the only time Southampton have avoided defeat after falling behind in a league game this season.
They have dropped 23 points after taking the lead, the highest total in the division this term.
Saints have kept just two clean sheets in the league this season, conceding three goals or more on 16 occasions.
Their average expected goals against figure this season is 2.4 per game, the highest on record in a Premier League campaign (such data exists from 2012-13).
Ivan Juric has won one and lost 11 of his 12 Premier League matches. He could become the third manager to lose each of his opening seven home fixtures in the competition, after Mick McCarthy and Vincent Kompany.
Crystal Palace
Palace have not conceded an away goal since Christmas, keeping seven consecutive clean sheets on the road in all competitions.
They have won six successive away games in league and cup for the first time in their history.
Home and away, the Eagles have won five fixtures in a row in all competitions, their best run since a similar streak ended in April 2014.
They are vying to win four consecutive Premier League matches for the first time since June 2020.
Ismaila Sarr has four goals in his last four club games in all competitions, having previously gone 10 appearances without scoring.