Team news
Liverpool right-back Conor Bradley could make his comeback from the hamstring injury he suffered against Aston Villa in mid-February.
Ryan Gravenberch is set to be available despite withdrawing from international duty because of injury, while goalkeeper Alisson Becker suffered concussion while playing for Brazil and will be assessed.
Everton pair Iliman Ndiaye and Dwight McNeil have resumed full training, though it's unclear if either of them will be involved on Wednesday.
Vitalii Mykolenko has overcome a thigh injury sustained on international duty with Ukraine.
Match facts
Head-to-head
Liverpool have won each of the past three Premier League Merseyside derbies at Anfield by a 2-0 scoreline. They've not earned four league victories in a row at home to Everton since a five-match spell between 1990 and 1994, while they've never done so without conceding.
Everton's solitary league victory at Anfield in 24 attempts since 1999 came in February 2021 (D9, L14)
This season's reverse fixture in February ended 2-2, meaning Everton are looking to avoid defeat in both league meetings with Liverpool for the first time since 2020-21.
Meetings between these two sides have produced a Premier League-high 25 red cards. Everton have received 17 of those, the most for one team against another in the division.
Liverpool
The Reds are unbeaten in 25 league games, the third longest top-flight run in their history.
They could become the first side in English top-flight history to score at least twice in as many as 27 of their opening 30 league matches in a season. Liverpool currently share the record with Everton, whose 26-game run took place in 1894-95.
Arne Slot's side had scored at least twice in 19 successive home games in all competitions, the longest run by any side in 90 years, before losing 1-0 to PSG in their most recent Anfield fixture.
They have kept a 12 league clean sheets this season, a joint high with Nottingham Forest prior to the midweek fixtures.
Mohamed Salah has been directly involved in eight goals in his last seven Premier League Merseyside derbies, scoring six times and providing two assists.
Everton
Everton's current nine-match Premier League unbeaten run – with four wins and five draws – is their longest since a similar tally in February 2017. They last went 10 league games without defeat in December 2013.
However, they have drawn five of their last six league fixtures. Everton's total of 13 top-flight draws this season is more than any other side.
The Toffees have scored a league-high 41% of their goals this season – 13 of 32 – from set-pieces other than penalties.
David Moyes has not won any of his 19 Premier League away games against Liverpool. It's the joint-most any manager has faced the same club without ever winning – a record he shares with himself, against Chelsea.