Follow live radio commentary from Sheff Wed v Leeds & Brentford v Bournemouth
Seven Premier League sides in second-round action
FT: Wolves 3-2 West Ham, Bournemouth 0-2 Brentford, Burnley 2-1 Derby, Sheff Wed 1-1 Leeds (3-0 on pens), Sunderland 1-1 Huddersfield (5-6 on pens)
Port Vale beat Birmingham, Stoke lose to Bradford & Cambridge knock out Charlton - all scores here
19 ties in total on Tuesday, with four more on Wednesday
Bournemouth 0-1 Brentford
Two substitutions for Bournemouth as they look to turn this one around.
Marcos Senesi replaces Bafode Diakite in defense, while Antoine Semenyo comes on for debutant Ben Gannon-Doak.
Brentford remain unchanged.
Sheff Weds 0-0 Leeds
Spirited performance by the Championship hosts. Leeds have been flat.
Image source, Getty ImagesSheff Weds 0-0 Leeds
That's sooooooo close!
Sheffield Wednesday win a free-kick about 20 yards out and Jamal Lowe is standing over it.
Up he steps and...it drops agonisingly wide of the post.
We're back under way in most of our 19:45 BST kick-offs.
Sheff Weds 0-0 Leeds
A rare attempt on target but Noah Okafor's shot is comfortable for Sheffield Wednesday goalkeeper Ethan Horvath.
Comment at the top of this page, WhatsApp on 03301231826 or text 81111 (UK only, standard message rates apply)
West Ham need clinical Wilson up top. Take a CM off and put Wilson on with Bowen and Paqueta in behind him.
Riyaadh - London
Image source, Getty ImagesSheff Weds 0-0 Leeds
78.6% possession for Leeds but still no goals with half-time rapidly approaching.
Zak Bradshaw (55 mins)
The players are queuing up to extend the Cambridge lead.
It's sloppy defending from the Championship side as Cambridge have multiple bites at the cherry.
Zak Bradshaw finishes it off to get the League Two side closer to the third round.
Comment at the top of this page, WhatsApp on 03301231826 or text 81111 (UK only, standard message rates apply)
Leeds are making really hard work of it against Sheff Weds juniors. If they keep this up I won't be watching the second half.
Steve - Darlington
Leeds poor, no passion and average players who want to go backwards.
Chris - Doncaster
Tomas Soucek
Image source, Getty ImagesJust what Graham Potter needed!
Tomas Soucek, who has been such a servant for West Ham, pops up with the equaliser as the Hammers pounce early in the second half.
Much better by West Ham after that 5-1 mauling by Chelsea last Friday.
Burnley 1-1 Derby
All square at Turf Moor.
Bournemouth 0-1 Brentford
Bournemouth have seen much more of the ball but it's Brentford who have taken their chance.
Fabio Carvalho's side-footed finish in the 34th minute is the difference.
The hosts will have to find a way to get through the visitor's compact low block in the second half if they are to avoid an early exit from the competition.
Wolves 1-0 West Ham
Back under way at Molineux.
Sunderland 0-1 Huddersfield
Still no shots on target for Sunderland against League One Huddersfield.
Massimo Luongo (33 mins)
Millwall lead their Championship counterparts after poor set-piece defending from Coventry.
Summer signing Massimo Luongo sneaks in and finishes it off smartly.
Image source, Getty ImagesJaheim Headley (45 mins)
Trouble for Tom Brady's Birmingham City!
League One Port Vale get the first goal of the game, and they thoroughly deserve it.
Ryan Croasdale with a pinpoint cross into the box and Jaheim Headley heads it past James Beadle.
Image source, Getty ImagesBrendan Sarpong-Wiredu (45 mins)
Late in the half Plymouth are level!
It's a fantastic header from close range by Brendan Sarpong-Wiredu after a lovely free-kick from left-back Matthew Sorinola.
Sheff Weds 0-0 Leeds
A big chance for Leeds to take the lead but United States goalkeeper Ethan Horvath does ever so well to claw away an attempt by fellow countryman Brenden Aaronson, who looked certain to put the Premier League club ahead from close range.
Bournemouth 0-1 Brentford
Bournemouth push again as Alex Scott sends a dangerous cross curling in towards the back post which causes panic for the Brentford defence, but the Bees just about manage to clear the danger.
Cameron Archer (42 mins)
Cameron Archer gives Southampton the lead in this all Championship tie.
It's a fantastic finish from Archer, who curls it around the defender and finds the top corner.
Image source, Getty Images
