Titans beat Seahawks in overtime; Tom Brady throws for another five touchdowns as Tampa Bay beat Atlanta
Cowboys beat Chargers at the death; Cardinals edge thriller with Vikings
Patriots & Bills are comfortable winners in AFC East divisional match-ups
Ravens get the better of Chiefs at Baltimore in late game
49ers, Raiders, Bears, Browns, Rams, Broncos & Panthers win the other early games
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Los Angeles Rams 24-21 Indianapolis Colts
How about this for a response - Matt Stafford and Cooper Kupp look like instant BFFs and they hook up for a big 44-yard gain before connecting on a 10-yard score on the very next play.
And just like that, in two plays, LA are back in front.
San Francisco 49ers 14-3 Philadelphia Eagles
That was a 16-play drive by the 49ers, lasting almost nine minutes, and now the Eagles must be wondering what happened with this game.
They were well on top late in the second quarter, without having the points to show for it, and Jimmy Garoppolo was struggling.
Now the 49ers quarterback has thrown for 181 yards, completed 21 of 29 passes and thrown for one touchdown while rushing for another.
Houston Texans 21-24 Cleveland Browns
How about that back-up QB, rookie Davis Mills eh? He's got Houston back in the game with a quick slant to Brandin Cooks for the touchdown.
It looks simple and Cooks is too quick for the Browns defenders to get anywhere near him, but it's surprisingly difficult for the QBs to get the ball out of their hands so quick under pressure.
Nice throw rookie.
San Francisco 49ers 14-3 Philadelphia Eagles
San Francisco raced clear last week and were comfortable against the Detroit Lions before holding on in a nervy finish. They're having to grind it out this week though.
Jimmy Garoppolo spreads it round on this drive, which continues into the fourth quarter, before Elijah Mitchell forces his way over from a yard... or did he? The touchdown's chalked off.
No matter, on the very next play Garoppolo gets in from a quarterback sneak for his first rushing touchdown in two years.
Los Angeles Rams 17-21 Indianapolis Colts
Look away now Rams fans...
Ashton Dulin has officially been credited with a ZERO yard fumble recovery touchdown but what you really need to know is just how bad that special teams play was by LA.
The long snapper hit the personal protector's arm with the ball when he was looking to fire it back to the punter, from there it's just a scramble and the Colts end up with the score, and the lead.
A comedy of errors.
Buffalo Bills 21-0 Miami Dolphins
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Buffalo Bills 21-0 Miami Dolphins
Josh Allen and the Bills have had it all their own way in Miami - as they usually do with their winning streak against the Dolphins set to continue after Dawson Knox caught the touchdown pass.
New Orleans Saints 0-17 Carolina Panthers
Another big name getting injured on a brutal Sunday in the NFL...
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Cincinnati Bengals 3-14 Chicago Bears
After 199 passes without an interception, Joe Burrow finally throws another pick, but it's the big one as it's turned into a pix sic by Roquan Smith.
The big linebacker ghosts under thr Burrow radar, grabs the ball and shows a nifty bit of footwork actually for big guy before also showing so wheels to race into the end zone.
Nobody really fancied trying to stop the big fella anyway...
San Francisco 49ers 7-3 Philadelphia Eagles
It's been a brutal day so far in the NFL...
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Houston Texans 14-24 Cleveland Browns
Chase McLaughlin splits the uprights as Cleveland just pull away now to a 10-point lead. It's been far from easy, though, even though Texans QB Tyrod Taylor has been forced out of the game and third-round rookie Davis Mills is now under centre.
San Francisco 49ers 7-3 Philadelphia Eagles
Miles Sanders makes three straight runs up the gut to move the chains for the Eagles.
Again the drive peters out for Philly though. After 11 plays, they have to punt.
Los Angeles Rams 17-14 Indianapolis Colts
Game on in Indy!
Carson Wentz is scrapping for his life here and he does well not only to find Zach Pascal in the end zone for the touchdown but also to hit tight end Jack Doyle for the two-point conversion to really put the squeeze on the Rams.
The Colts haven't really been that in the game but they're right in it now. Looks like two good, solid teams at work here.
Certainly two play-off teams.
Los Angeles Rams 17-6 Indianapolis Colts
You're outta here!
The refs don't quite have the gusto that the baseball officials have when tossing someone out of the game, but nevertheless, Kenny Young is out for the Rams.
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Cheers Michael, cheque's in the post!! And no, we'll be signing off just before the Chiefs-Ravens game I'm afraid.
Some mouth-watering prospects before that though... Kyler Murray, Tom Brady, Russell Wilson and Dak Prescott are all in action in the later games.
San Francisco 49ers 7-3 Philadelphia Eagles
San Francisco grabbed the game's first touchdown right before the break but defences are now well and truly back on top in Philly.
The Eagles and the 49ers are forced to punt on their first possessions of the second half.
Houston Texans 14-21 Cleveland Browns
What does a sixth-round pick number 211 in the NFL Draft get you? Well, it gets you this monster 33-yard touchdown from rookie Demetric Felton.
Who? Yep, that was my response too, but in a team with Nick Chubb and Kareen Hunt it's Felton who has shown them the way with this sprinting, juking, twisting, elusive run that I've run out of adjectives for.
What I do know is that just seconds after Harris ran in that brute of a score for the Patriots that's a whopping back-to-back touchdown sequence.
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New England Patriots 19-3 New York Jets
Damien Harris runs the ball here like a deeply angry man, and it works a treat as he just bounces through the line, bounces off would-be tacklers and bounces his way into the end zone.
He gets the last couple of yards with the help of some of his mates behind him and that's one of the hardest-earned 26-yard scores you'll ever see.
I'll get a few bruises just writing about that touchdown it was so brutal!
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New Orleans Saints 0-17 Carolina Panthers
On the team where Cam Newton won the MVP award in 2015, this is some effort...
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New England Patriots 13-3 New York Jets
Image source, Getty ImagesFeels like I should be using the ugly emoji for this post, but it's poor old Zach Wilson again who has just thrown his FOURTH interception of the day for the Jets.
I say old, he's 22 and a starting quarterback in the NFL so I've got limited sympathy, but his head must be spinning right now. That's what evil genius Bill Belichick usually does with rookie QBs, though. Now that guy has no sympathy for them whatsoever!
It just shows that these rookie QBs still need a decent team around them to shine - Zach Wilson certainly does not have that right now.