Extended jeering from the consistently vocal Fener fans as United put together a long, long spell of play, some neat one-touch stuff on the fringe of the area and Juan Mata runs on to it - it's well cut out though. Paul Pogba laces a drive in from 25 yards and a defender wears it square on the forehead. 

Image source, Reuters

Wires crossed.

Juan Mata knocks a ball far post when Anthony Martial has burst towards the near.

Decent idea from the Frenchman though.

Southampton

Southampton manager Claude Puel: "It is very hard to lose this game because we have had control of the game every time. 

"I think we are unlucky because we played a very good game with quality and had many, many, chances and it is a big disappointment tonight.

"My players gave a good performance important but now we need to recover and think about the Premier League but for the moment it is hard and disappointing for this club."

Image source, Getty Images

Image source, Rex Features

Also in among the Fenerbahce fans is former Middlesbrough and Stoke striker Tuncay Sanli. 

He is still sporting that curly mop of locks as well.

Simon Stone
BBC Sport

A few interesting faces in the Manchester United directors' box this evening.

A non-playing player - Henrikh Mkhitaryan.

An international manager - Roberto Martinez

A former international manager - Sam Allardyce.

The former England manager is sat a few seats along from one of the men who appointed him; former United chief executive and current FA vice-chairman David Gill.

Image source, Reuters

Wayne Rooney dropping deep again and Paul Pogba takes the hint and bombs on towards the penalty area.

Rooney's ball towards the France international is cut out by Martin Skrtel with a hefty hoof into the stands.

Image source, Reuters

Manchester United are dominating the ball in the early stages. Full-backs Matteo Darmian and Luke Shaw are both pushing on deep into the Turkish visitors' half.

Wayne Rooney's first involvement is to reverse backside first into Simon Kjaer as he attempts to hold up the ball on halfway.

Kjaer hauls him down and it is a United free-kick. 

Image source, Reuters

Eric Bailly very nearly takes Jose Mourinho's face off with a shanked long ball that flies off the side of his boot and over the home dug-out.

A hand of apology from the Manchester United centre-back to his boss.

Image source, Getty Images

We are up and running at Old Trafford. 

Mark, Berkshire: Saints problem all season has been their inability to hit a barn door with a banjo in front of goal, paid for that continued failure tonight.

The two teams are being called together for a jumbled-up group shot to highlight Uefa's anti-racism campaign.

The same has been done at all the Champions League and Europa League matches this week.

Image source, Rex Features

Fenerbahce centre half Martin Skrtel is wearing a mask to protect his face. It is a little Hannibal Lecter.

He will be a pantomime villain anyway as a former Liverpool player. Might as well play up to it.

Robin van Persie has been given a rousing reception as he strolls out onto the Old Trafford turf once more.

Image source, Getty Images

Image source, Rex Features

Wayne Rooney has been front and centre of the Manchester United warm-up at Old Trafford tonight.

How important is tonight in his United future?

Jose Mourinho is not a man of taking tough decisions over big names. 

Samuel Oj: Hoping Rooney can bag some goals tonight & improve his confidence

AADZ: Memphis can't buy a game! Unfortunate that 2 managers have not given him a chance.he should leave! Waste of talent on the bench 

Sho Rahman: Don't get what's going on with Mkhi. Was the best No. 10 in the world last season, apparently fit, and not even on the bench. 

Image source, Reuters

Dundalk have a chance to make fresh history in their pioneering run in the competition. The Lilywhites became the first Irish side to win a group-stage game in European competition by beating Maccabi Tel-Aviv in September. Tonight they welcome a Zenit St Petersburg squad that includes former Chelsea full-back Yuri Zhirkov, ex Manchester City midfielder Javi Garcia and Belgium international Axel Witsel to the Tallaght Stadium and victory would take them top of Group D.

Elsewhere watch out for 19-year-old Jamaican sensation Leon Bailey whose Genk side are up against Athletic Bilbao in Group F. Bailey, who has five goals in his last eight games, is reportedly a target for Manchester United., external

There is another milestone coming up in the Francesco Totti's long and illustrious Roma career tonight. The 40 (forty!)-year-old playmaker, who signed a one-year deal in the summer to extend his time at the club to 25 seasons, makes his 100th European appearance against Austria Vienna.

Image source, Getty Images

Image source, Getty Images

Image source, Getty Images

Image source, Getty Images

September 2004, an 18-year-old Wayne Rooney hit a hat-trick against Fenerbahce on his Manchester United debut.

12 years on, will it be more of the same tonight?

Read our match report of Rooney's Manchester United debut here.

Southampton will head home wondering how on earth they lost that one. But their travelling army still sing out in fine voice.