Arsenal make nine changes from their Europa League game as they revert in the most part to their Premier League XI. But Laurent Koscielny is out with injury while Mesut Ozil is also still deemed unfit. Rob Holding and Alex Iwobi come into the side that beat West Brom on Monday. Alexis Sanchez and Alexandre Lacazette start up front.

Arsenal XI: Cech, Holding, Mustafi, Monreal, Bellerin, Ramsey, Xhaka, Kolasinac, Iwobi, Sanchez, Lacazette.

Subs: Mertesacker, Wilshere, Giroud, Ospina, Walcott, Maitland-Niles, Elneny.

Brighton make three changes with injuries and suspension meaning Izzy Brown plays as a central striker.

Striker Tomer Hemed is serving the first of a three-game ban for violent conduct and misses out while Anthony Knockaert and Markus Suttner are also replaced by Gaëtan Bong and club-record summer signing José Izquierdo, who is making his first Premier League start.

Brighton XI: Ryan, Saltor, Duffy, Dunk, Bong, March, Stephens, Propper, Izquierdo, Gross, Brown.

Subs: Krul, Knockaert, Murray, Goldson, Schelotto, Suttner, Molumby.

Arsenal

Arsenal manager Arsene Wenger on Brighton: "I think it will be difficult to break them down because they are very well organised, they are very disciplined as well.

"Their team keeps the ball well and from what I've seen they have a good technical quality, they try to play everywhere and it is a different challenge for us.

"We have done very well at home until now, so we know that it is absolutely vital for us."

Simon Brotherton
MOTD commentator

On paper, and with many of their big names rested in Thursday's Europa League match in Belarus, this looks like it should be a straightforward home win for Arsenal.

But Brighton manager Chris Houghton knows what it's like to upset odds at The Emirates. He was in charge of Newcastle the last time Arsenal lost at home to a newly-promoted team seven years ago, with the Magpies recording a 1-0 win.

Brighton will likely need to keep it tight to stand a chance this time too, with scoring goals likely to be their biggest immediate problems.

Three games, three kick-off times. Settle in for another long day at the Premier League coal face.

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Arsenal v Brighton (12:00 BST)

Everton v Burnley (14:15 BST)

Newcastle v Liverpool (16:30 BST)

Brighton & Hove Albion

Brighton make three changes from the win over Newcastle - in come Gaetan Bong, Jose Izquierdo and Izzy Brown.

Arsenal

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Image source, Getty Images

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