Wolves defender Wily Boly is suspended following his sending off against Everton, so Jesus Vallejo could make his Premier League debut.

Wing-back Matt Doherty is in contention despite missing international duty with Ireland because of minor surgery.

Chelsea defender Antonio Rudiger might make his first appearance of the season after recovering from a knee injury.

Pedro returns after missing one game with a hamstring problem, but N'Golo Kante remains out with an ankle injury.

Mateo Kovacic is fit despite withdrawing from international duty with Croatia.

Chelsea

Chelsea boss Frank Lampard: "Antonio Rudiger will have an important role to play. I know how important he has been for the club with his personality, character and quality as an international defender.

"We have missed him as we have missed a few front line players... leadership is important in a team, particularly when everyone is saying how young we are. I don't want a young team for the sake of it.

"I want leaders within that and Rudiger has to take on that responsibility."

Image source, Getty Images

Tom Rostance
BBC Sport at Anfield

Liverpool make two changes for the resumption as Roberto Firmino and Jordan Henderson both step down to the bench. Firmino played an hour in LA on Wednesday night for Brazil - their 17-game unbeaten run came to an end against Peru - so gets a bit of a breather, with Divock Origi coming in. Alex Oxlade-Chamberlain gets a chance in midfield.

Liverpool XI: Adrian, Alexander-Arnold, Matip, Van Dijk, Robertson, Wijnaldum, Oxlade-Chamberlain, Fabinho, Mane, Salah, Origi

Image source, BBC Sport

Newcastle make just one change from the side held by Watford last month - former Liverpool midfielder Jonjo Shelvey replaces the injured Sean Longstaff. There's still no sign of Andy Carroll.

Newcastle XI: Dubravka, Dummett, Schar, Lascelles, Shelvey, Joelinton, Hayden, Willems, Krafth, Almiron, Atsu

Image source, BBC Sport

Jurgen Klopp is obviously trying to rotate his internationals. Are you surprised Xherdan Shaqiri hasn't been given a go?

And will Jonjo Shelvey be able to have an impact against his old club? Tweet me using #bbcfootball or text 81111 (UK only).

There are two changes to the Liverpool team as Roberto Firmino drops to the bench. Divock Origi comes into the attack. Jordan Henderson is also replaced by Alex Oxlade-Chamberlain in midfield.

Newcastle make just one change. Jonjo Shelvey replaces the injured Sean Longstaff in midfield.

Full team news to come.

Image source, Getty Images

Image source, BBC Sport

There is nothing wrong with the Blues' attacking play under Frank Lampard, but they have some improving to do at the back.

I am confident Lampard will get it right though. This is a tricky one for Chelsea because I really rate Wolves and the way they play, but I just have a feeling the Blues will edge it.

Prediction: 1-2

Lawro's full predictions v MOTDx stars Chelcee Grimes, Craig Mitch and Reece Parkinson

Robyn Cowen
BBC Sport

There's a real feeling of freshness to both Brighton and Burnley in the early part of the season.

The arrival of Graham Potter has brought new ideas and a more expansive style to Brighton. There's just one thing that's missing: a win at the Amex - the home support haven't seen a victory since March.

As for Burnley, unleashed from the shackles of the Europa League, they're already three points better off than at this time last year.

They also have a striker in red-hot form in Ashley Barnes., external

If we do have a winner on Saturday, the loser could see their early-season optimism vanish very quickly.

Team news coming up from Anfield in a few minutes...

Chelsea's most recent league victory against Wolves was at Molineux on 2 January 2012, when Frank Lampard scored the decisive goal in the 89th minute.

Nuno Espirito Santo's side are unbeaten in 10 home league games since losing to Crystal Palace in January (W6, D4).

Chelsea have conceded nine Premier League goals this season - only Norwich, with 10, have a worse record.

Image source, BBC Sport

The road signs in Manchester have been brilliant this season but this one was definitely done by a Manchester City fan...

Tom Rostance
BBC Sport at Anfield

It's so sunny I can hardly see my laptop screen... First world problems.

Image source, BBC Sport

The transfer deadline, the international break, school holidays - it's always a fragmented start to the Premier League season.

But after a two-week break, the sides are back in action today. Are you up to speed with proceedings?

Take our quiz to find out...

Image source, Getty Images

Steve Wilson
Match of the Day commentator

Last time I saw Wolves play at home to Chelsea was an FA Cup fifth-round tie in early 2017. Wolves were just outside the relegation zone in the Championship and the visitors topped the Premier League.

It would have been tough to conceive that within 18 months you could make a case for Chelsea being underdogs at Molineux.

Not that Nuno Espirito Santo will see it like that - after all, Wolves still haven't won a league game this season despite six wins from six in Europa League qualifying.

Chelsea's very youthful side have - as you might expect - shown both promise and naivety. This will not be dull.

Burnley

Burnley manager Sean Dyche on Danny Drinkwater: "He's old enough and wise enough to know you do whatever you can to try not to get into scrapes but sometimes it happens.

"He is part of us. We have to work with him and help him get realigned to where he was and where he wants to be. We have talked to him and the rest will remain private."

Image source, Getty Images

Image source, BBC Sport

You can already see how Brighton are a more adventurous side this season with Graham Potter in charge. Even in their defeat by Manchester City last time out, they had a bit of a go.

I think the players appreciate having the freedom to attack, and the Seagulls fans will definitely enjoy watching them.

It will be the same approach against Burnley, but I think the Clarets will be a tough nut to crack - they usually are.

Prediction: 1-1

Lawro's full predictions v MOTDx stars Chelcee Grimes, Craig Mitch and Reece Parkinson

Tom Rostance
BBC Sport at Anfield

Image source, BBC Sport

Short sleeves and sunglasses sort of September morning in Stanley Park as the Premier League makes a welcome return.

Image source, BBC Sport

Liverpool duo James Milner and Joe Gomez are both pushing for recalls but keeper Alisson and Nathaniel Clyne are still missing.

Midfielder Naby Keita is expected to return to training in the coming days following a pre-season calf injury but won't be available.

Sean Longstaff is out for Newcastle after twisting his ankle in training.

Matt Ritchie, Allan Saint-Maximin, Andy Carroll, Dwight Gayle, DeAndre Yedlin and Florian Lejeune also remain unavailable.

This will brighten up your day.

Remember when Sadio Mane and Mo Salah had that little quarrel? Well, the Egyptian settled it once and for all with this glorious tweet on Friday evening.

It's a busy one.

Seven games and 14 teams in action. Here are the fixtures taking place at 15:00 BST. Liverpool v Newcastle is up first, followed by Norwich v Manchester City.

Image source, BBC Sport

It's been 13 long days but the Premier League is finally back!

And it's league leaders Liverpool who open the weekend with a home fixture against Newcastle United, kicking off at 12.30 BST.

Title rivals Manchester City are in action this evening, while other top four teams Leicester and Crystal Palace have tough away trips against Manchester United and Tottenham respectively.

Norwich are the only team from the bottom three playing today - they take on Pep Guardiola's side at 17:30 BST.

Image source, Getty Images